Abstract:Objective To summarize the characteristics and sources of infection risk of Bacillus cereus (B. cereus) septicemia in low birth weight (LBW) infants, and provide reference for infection prevention and control. Methods Characteristics of 3 LBW infants with B. cereus septicemia were reported and analyzed, relevant literatures were searched for systematically summarizing the characteristics and sources of infection risk of B. cereus septicemia in infants. Results Among 3 LBW infants reported in this paper, 2 died and 1 was cured. No clear infection source was found in the environment through object surface sampling analysis. A total of 43 cases were reported in the previous literatures, 41 cases had reported on survival status, the mortality was 36.6%. The main risk factors for infection were auxiliary ventilation, umbilical vein catheterization or central vein catheterization and enteral feeding. In the reported 3 cases with clear sources of infection, the pathogens came from mother’s milk, decoration area, surface of infant incubator and ultrasonic probe. Conclusion Premature LBW infants with B. cereus septicemia have high mortality and poor prognosis, which is a healthcare-associated infectious disease seriously threatening the life and health of LBW infants. Neonatal intensive care unit (NICU) and relevant departments of healthcare-associated infection (HAI) management need to pay attention to the prevention, monitoring, early detection, as well as active diagnosis and treatment of HAI caused by this bacteria.