蜃楼弗朗西斯菌血流感染1例及文献复习

Francisella philomiragia bloodstream infection: one cases report and literature review

摘要:

蜃楼弗朗西斯菌感染是罕见的感染疾病。本文报告1例蜃楼弗朗西斯菌血流感染患者,复习国内外相关文献资料,总结分析感染患者临床特征。研究发现,慢性肉芽肿病、溺水、血液系统疾病、糖尿病、肾移植、风湿病、嗜酒等免疫功能低下或免疫屏障受破坏者是蜃楼弗朗西斯菌易感人群,接触咸水是其危险因素。以氨基糖苷类、氟喹诺酮类、多西环素为基础的联合抗感染方案可提高治疗成功率。

Abstract:

Francisella philomiragia (F. philomiragia) infection is a rare infectious disease. This article reported one case of bloodstream infection of F. philomiragia. Relevant literatures from at home and abroad were systematically reviewed, and clinical characteristics of infected patients were summarized and analyzed. The research found that people with chronic granulomatous disease, drowning, blood system diseases, diabetes, kidney transplantation, rheumatism, alcoholism, and other immunocompromised or immune barrier damaged people are susceptible to F. philomiragia. Salt water exposure is a risk factor. The combined anti-infection scheme based on amino-glycosides, fluoroquinolones and doxycycline can improve the success rate of treatment.