Abstract:Objective To investigate the status of human immunodeficiency virus (HIV) infection among voluntary blood donors(VBDs) in Hainan area, provide evidence-based references for optimizing the recruitment of blood donation and strengthen management of blood safety. Methods Routine HIV test was carried out on blood screening specimens of VBDs in Hainan area from 2013 to 2017, and data of HIV positive donors were analyzed retrospectively. Results A totla of 470 975 VBDs were detected, of which 103(0.22‰) were confirmed HIV positive. There was no significant difference in HIV positive rate among VBDs in different years and regions (both P>0.05). Among 103 confirmed HIV positive VBDs, 65 (63.11%) were in 18-30 year-old group, with a positive rate of 0.33‰. There was a significant difference in the positive rate of HIV among VBDs of different age groups (χ2=22.379,P<0.001). Among 95 confirmed HIV positive VBDs, 95 were male and 8 were female, positive rate of HIV in male blood donors was higher than female (0.29% vs 0.06‰, χ2=23.003,P<0.001). The main occupation types of HIV positive persons were employees (n=20, 19.42%), followed by students (n=16, 15.53%) and unemployed persons(n=6, 5.83%). Conclusion HIV infection among voluntary blood donors in Hainan area is still serious, to ensure blood safety, multiple measures should be taken, including the intervention before blood donation, taking more advanced detection technology and establishing internet database.