Abstract:ObjectiveTo understand the current situation and characteristics of occupational exposure(OE) among health care workers(HCWs), and provide basis for making preventive measures. MethodsSelfdesigned questionnaire about OE was adopted, OE among all HCWs in a hospital in JanuaryDecember 2015 were surveyed and statistically analyzed. ResultsA total of 1 888 HCWs were surveyed, there were 304 cases of OE, the mean OE rate in the whole hospital was 16.10%; OE occurred 370 times(19.60%). Doctors, trainees，and HCWs who worked for≤1 year had relatively higher OE rates, which were 23.18%(102/440), 17.88%(49/274), and 18.34%(95/518) respectively. Sharp injury is the main OE mode, accounting for 83.24%（n=308）, sharp injuries mainly occurred before disposing the used devices and during the process of use, accounting for 37.99%(n=117) and 36.69%(n=113) respectively. Among 370 times of OE, 315 could be traced to the sources of exposure. Among the known exposure sources, OE of bloodborne pathogens accounted for 24.13% (n=76). 59 of 370 times of OE implemented complete local treatment and reporting procedures, reporting rate of OE was 15.95%. ConclusionHospital should take comprehensive measures to promote occupational safety precaution, and reduce the incidence of OE.