Distribution and antimicrobial resistance of pathogens causing wound infection in army officers and soldiers in a military hospital

Abstract:

ObjectiveTo understand the distribution and antimicrobial resistance of pathogens causing wound infection in army officers and soldiers following military training injury, and provide reference for antimicrobial use in clinical antiinfection treatment. MethodsWound secretion from injured army patients who were admitted to a military hospital between January 2014 and June 2015 was performed bacterial culture and antimicrobial susceptibility testing. Results647 pathogenic bacteria strains were isolated from 1 029 wound secretion specimens , isolation rate was 62.88%, the top 6 isolated bacteria were Staphylococcus aureus（S. aureus, 29.99%, n=194）, Escherichia coli（E. coli, 19.32%，n=125）, Pseudomonas aeruginosa（19.17%，n=124），Enterococcus spp.（13.60%，n=88），Klebsiella pneumoniae(K. pneumoniae, 7.73%，n=50）, and  Acinetobacter baumannii （A. baumannii, 5.87%，n=38）. S. aureus and Enterococcus spp. had high susceptibility to vancomycin, linezolid , and daptomycin (resistance rates ≤3.41%）, 44.33% of S. aureus were methicillinresistant, 2.27% of Enterococcus spp. were vancomycinresistant . E.coli and K. pneumoniae had high susceptibility rates to piperacillin/ tazobactam (resistance rates were 1.60% and 0 respectively), except A. baumannii, resistance rates of gramnegative bacteria to carbapenems were all low (resistance rates ≤4.00%）. ConclusionMilitary clinicians should select appropriate antimicrobial agents according to antimicrobial susceptibility testing results, reduce the disability rate due to infection in trauma patients, and provide clinical support for the treatment of the wounded.