Abstract:ObjectiveTo evaluate whether there is a correlation among plasma levels of procalcitonin (PCT), Nterminal probrain natriuretic peptide (NTproBNP) and cardiac troponin T (cTnT) in patients with sepsis, as well as significance to prognosis of patients. Methods48 patients with sepsis who were admitted to the intensive care unit of a hospital between September 2014 and March 2015 were chosen for study, patients were divided into severe and mild sepsis groups according to the disease condition, plasma levels of PCT, NTproBNP, and cTnT were detected, mortality of patients were analyzed statistically, relation between plasma levels of PCT, NTproBNP, cTnT and patients’ death were compared. ResultsThe plasma levels of PCT, NTproBNP and cTnT in severe sepsis group were significantly higher than those in mild sepsis group (all P＜0.05); mortality of mild sepsis group was significantly lower than that of severe sepsis group (10.53% vs 41.38%, P＜0.05); Levels of PCT, NTproBNP and cTnT levels in died patients were all higher than surviving patients ( all P<0.05); levels of PCT and NTproBNP, NTproBNP and cTnT were positively correlated respectively (rs= 0.337, P＜0.05; rs＝0.456，P=0.001, respectively ), while PCT was not significantly correlated with cTnT. Plasma levels of PCT, NTproBNP, and cTnT were all correlated with the prognosis of patients (P＜0.05), and is helpful for judging the prognosis of patients, combination of three indexes had better prognostic value for the prognosis.ConclusionCombination detection of plasmid levels of PCT, NPproBNP, and cTnT can assess the severity of infection in patients with sepsis, and preliminarily judge the prognosis of patients with sepsis.