Abstract:ObjectiveTo understand the results and characteristics of targeted monitoring of healthcareassociated infection (HAI) in an intensive care unit (ICU) of a tumor hospital, so as to provide scientific basis for formulating measures of prevention and control of HAI.MethodsPatients who admitted to an ICU from January to December 2013 were performed targeted monitoring, incidence of HAI was adjusted with an average severity of illness score (ASIS), three types of invasive procedurerelated infection, distribution of pathogens, and multidrugresistant organisms were monitored.ResultsA total of 455 patients were monitored, the total patientdays were 2 483 days, 52 cases of HAI occurred, incidence of HAI was 11.43%,incidence of HAI per 1 000 patientdays was 20.94‰, after the adjustment with ASIS,incidence of HAI per 1 000 patientdays was 6.29‰. The main infection site was respiratory system(63.46%), followed by urinary system(19.23%); Incidence of ventilatorassociated pneumonia per 1 000 ventilationdays, catheterrelated bloodstream infection per 1 000 catheterdays, and catheterassociated urinary tract infection per 1 000 urinary catheter days were 12.08‰, 0.95‰, and 4.07‰ respectively. A total of 181 pathogenic isolates were detected, 74.59% (n=135) of which were gramnegative bacteria, 18.23%(n=33) were grampositive bacteria, and 7.18%(n=13) were fungi; 18.23%(n=33) were multidrugresistant strains.ConclusionICU is the high risk department of the occurrence of HAI, the main infection is respiratory tract infection, the major pathogen is gramnegative bacteria. Targeted monitoring can timely reflect the deficiency in infection control practice, is helpful for formulating effective prevention and intervention measures, and reducing the occurrence of HAI.