Abstract:ObjectiveTo explore the risk factors and prognosis of hospitalized patients with bloodstream infection due to carbapenemresistant Acinetobacter baumannii(CRAB).Methods163 patients with CRAB bloodstream infection from 2010 to 2013 were conducted retrospective casecontrol study, 68 patients with bloodstream infection due to carbapenemsusceptible Acinetobacter baumannii(CSAB) during the same period were as control group.ResultsThe independent risk factors for CRAB bloodstream infection were stay in intensive care unit(ICU) (OR,1.27［95%CI,5.55-22.89］) and emergency department(OR,3.57 ［95%CI,1.67-7.62］) before infection. Patients with CRAB bloodstream infection had lower 28day survival rate than those with CSAB bloodstream infection(66.17% vs 96.95%，χ2=15.71,P＜0.001). The independent risk factors for influencing prognosis of Acinetobacter baumannii bloodstream infection were infection of CRAB (HR 95% CI,3.01-67.28), blood disease(HR 95%CI, 3.77-25.97), cardiac insufficiency(HR 95%CI,2.10-20.41), stay in ICU(HR 95%CI, 1.01-5.28),and age(HR 95%CI,1.01-1.04).ConclusionThe independent risk factors for CRAB bloodstream infection are stay in ICU and emergency department before infection, CRAB bloodstream infection is risk factor for influencing prognosis of patients.