Effect of antimicrobialimpregnated incise drape on preventing surgical site infection following neurosurgical operation

Abstract:

ObjectiveTo investigate the  effect of antimicrobialimpregnated incise drape on preventing surgical site infection(SSI)  following  neurosurgical operation.MethodsPatients undergoing neurosurgical operation from January to December 2012 were divided into two groups: antimicrobialimpregnated incise drape group(group A) and  general incise drape group(group B). The occurrence of SSI and risk factors for SSI were analyzed.ResultsPercentage of drape lifting at the wound edge in group A was lower than group B(38.3%［98/256］ vs 96.88% ［248/256］, χ2=200.57，P＜0.01）. Among 512 patients, SSI rate was 3.32%(n=17), SSI rate  in group A was lower  than group B(1.56%［4/256］ vs 5.08%［13/256］, χ2= 7.93，P＜0.05 ). Multivariate analysis revealed that body mass index ≥24, perioperative hypothermia, smoking, perioperative length of hospital stay ≥5 days, and lack of drape use were independent risk factors for SSI  following  neurosurgical operation.ConclusionWhether antimicrobialimpregnated incise drape is used in neurosurgical operation is one of the independent risk factors for SSI  following  neurosurgical operation, it can effectively reduce the drape lifting rate and incidence of SSI, and  is recommended to be used in neurosurgical operation.