Risk factors for healthcareassociated infection in neurosurgical patients with hypertensive intracerebral hemorrhage

Abstract:

ObjectiveTo study the risk factors for healthcareassociated infection (HAI) in neurosurgical patients with  hypertensive intracerebral hemorrhage, and provide the basis for prevention and control of HAI. MethodsClinical data of 380 hospitalized patients with hypertensive intracerebral hemorrhage from January to December 2013 were analyzed.ResultsOf 380 patients, 36 (9.47%) had HAI. The top three sites of infection were lower respiratory tract (50.00%), surgical  incision (16.67%) and urinary tract(11.11%). A total of  51 pathogens were isolated, among which gramnegative bacilli and grampositive cocci accounted for 64.71%(n=33)  and 35.29% (n=18) respectively. The top three pathogens included Staphylococcus aureus (19.61%), Klebsiella pneumoniae (17.65%） and Escherichia coli (13.73%). Risk factors for HAI in hypertensive intracerebral hemorrhage patients were combined underlying diseases, invasive procedures, use of respirator, prolonged use of antimicrobial agents and long length of hospitalization(P<0.05).  ConclusionHAI rate is high in neurosurgical patients with  hypertensive intracerebral hemorrhage, surveillance should be intensified,  and effective preventive and control measures against risk factors  should be taken.

Key words:

neurosurgery; hypertension; intracerebral hemorrhage; healthcareassociated infection; risk factor