Abstract:ObjectiveTo evaluate the risk factors for healthcareassociated infection(HAI) in senile dementia patients, so as to adopt effective nursing measures to reduce the incidence of HAI. MethodsClinical data of 82 senile dementia patients aged≥60 years and hospitalized between January 2011 and June 2013 were analyzed retrospectively. ResultsOf 82 patients, 28 (34.15%) developed HAI. The main infection site was lower respiratory tract(n=15,53.57%), followed by urinary tract(n=6,21.43%). Univariate analysis revealed that risk factors for HAI in senile dementia patients were bedridden, long length of hospital stay , dysphagia, indwelling urinary catheter, irrational use of antimicrobial agents, combined with tumor, and hypoproteinemia (all P<0.05). The main isolated bacteria were gramnegative bacilli(n=40,62.50%) , the top three pathogens were Klebsiella pneumoniae(n=12,18.75%), Escherichia coli(n=10,15.63%), and Pseudomonas aeruginosa (n=8,12.50%). ConclusionRealizing the risk factors and common pathogens of HAI in senile dementia patients is helpful for taking effective measures to prevent and control the incidence of HAI .