Abstract:ObjectiveTo investigate the risk factors for imipenemresistant Pseudomonas aeruginosa (IRPA) infections in Xi’an, and provide reference for the control of IRPA infections .Methods103 IRPA patients who were hospitalized at 4 hospitals in Xi’an between February and October 2013 were randomly selected(case group),103 imipenemsusceptible Pseudomonas aeruginosainfected patients during the same hospitalization period were as control group, risk factors for IRPA infection were analyzed.ResultsUnivariate analysis revealed that old age, length of hospital stay≥4 weeks, chronic pulmonary diseases, stay in intensive care unit, mechanical ventilation, use carbapenems (imipenem, meropenem) 2 weeks before the isolation of IRPA ,and early combination of antimicrobial drugs were related risk factors for IRPA infection;Logistic multivariate analysis showed that length of hospital stay≥4 weeks（OR95%CI：1.44-139.73）, mechanical ventilation（OR95%CI：2.96-267.75）,and use carbapenems (imipenem, meropenem)2 weeks before the isolation of IRPA（OR95% CI：2.65-154.34）were independent risk factors for IRPA infection.ConclusionIRPA infection in patients in this area should be intervened to reduce risk factors for IRPA infection.