Abstract:ObjectiveTo investigate the occurrence and susceptibility factors of surgical site infection(SSI) in patients undergoing oralmaxillofacial surgery with microvascular freeflap reconstruction.MethodsFrom December 2010 to September 2011, a prospective survey was performed to monitor the susceptibility factors for SSI in 257 patients undergoing oralmaxillofacial surgery with microvascular freeflap reconstruction, the surveyed contents included age, sex, the nature of disease, American Society of Anesthesiologists(ASA) score, white blood cell, hematoglobin, length of hospital stay, length of surgery, types of incision, intraoperative blood loss and so on. Patients were followed up after 1, 3 and 6 months of operation,the occurrence of SSI at different stages were surveyed.ResultsOf 257 patients, 46 (17.90%) developed SSI, and all were deep wound infection,19 (41.30%) of whom had SSI during hospitalization period, and 27 (58.70%) were found through postdischarge followup investigation. Infection occurred 5-34 days after operation, the median time was 11 day. Monitoring of susceptibility factors showed that,except the duration of intraoperative antimicrobial use (≤110 min) was statistically significant (P<0.05), other factors were not statistically significant (P>0.05).ConclusionIncidence of SSI is high in oralmaxillofacial surgery with microvascular freeflap reconstruction, and mostly occur in patients after discharging from hospital. In order to reduce SSI effectively, clinical attention should be paid, postoperative followup should be intensified, intervention in susceptibility factors should be performed, and antimicrobial agents should be used rationally.