Abstract:ObjectiveTo investigate the drugresistance, drugresistant genes and prevalence of reducible clindamycin resistance of methicillinresistant Staphylococcus haemolyticus (MRSH) in Suzhou district of Anhui province.MethodsSusceptibility of 42 MRSH isolates to 16 kinds of antimicrobial agents were performed with ATB STAPH5 strip microdilute testing; drugresistant genes mecA,qacA/B/C,qacA,ermA/B/C,ermB and TetM in MRSH were detected with polymerase chain reaction; inducible clindamycin resistance was detected with Dtest.ResultsSensitive rates of 42 MRSH isolates to vancomycin and nitrofurantoin were both 100.00%, sensitive rates to rifampicin, minocycline, quinupristin/dalfopristin and teicoplanin were all >90%; resistant rates to gentamicin, norfloxacin and levofloxacin were all >70%, resistant rates to penicillin,oxacillin and erythromycin were all 100.00%. The positive rate of mecA,qacA/B/C, qacA, ermA/B/C, ermB and TetM gene was 100.00%(42 isolates), 64.29%(27), 59.52%(25), 40.48%(17), 28.57%(12) and 9.52%(4) respectively. 13 MRSH isolates were Dtest positive，30.95% of which was inducible drugresistance.ConclusionMRSH isolated from Suzhou district of Anhui province showed multidrug resistance, antimicrobial agents should be chosen rationally according to antimicrobial susceptibility testing results.