Clinical related factors of healthcareassociated Candida infection

Abstract:

ObjectiveTo realize the clinical characteristics of healthcareassociated Candida infection in a hospital.MethodsCase histories of inpatients who were infected with Candida from 2008 to 2009 were analyzed retrospectively.ResultsOne hundred and seventysix patients developed Candida infection from 2008 to 2009, which accounting for 7.73% of the total healthcareassociated infection; the most common infection site was lower respiratory tract (55.68%), the next was urinary tract(18.75%); the main fungi were Candida albicans and Candida tropicalis, which accounting for 58.52% and 23.86% respectively. The main underlying diseases before infection were respiratory (30.11%)and urological diseases (21.59%). The length of hospital stay, medical expense and mortality of patients infected with Candida were significantly longer or higher than that of the other patients during the same hospitalization period (P<0.05).ConclusionFor patients with the risk of Candida infection, it is important to use antimicrobial agents rationally, manipulate sterilely, and treat the primary disease actively; early diagnosis and early treatment is important measure for preventing and controlling the infection of Candida.

Key words:

Candida;healthcareassociated infection; risk factor; antimicrobial agents; drug resistance, microbial