Abstract:Objective To understand the prevalence characteristics of influenza and changes of influenza virus strains, and provide reference for the prevention and control of influenza in the province. Methods Surveillance data about influenza in Hunan Province from 2014 to 2023 were exported from China Influenza Surveillance Information System. Differences in the percentage of influenza-like illness (ILI) cases (percentage of influenza-like cases [ILI%] in outpatient and emergency department visits) among different years and different populations, as well as the positive rate of influenza virus in ILI specimens were compared. Results From 2014 to 2023, over 2.65 million cases of ILI were reported, with an ILI% of 4.70%. ILI% among different years presented statistically significant differences (P<0.001). People aged 0-14 years old were the main population with ILI, accounting for 82.90%. The positive rate of influenza virus in ILI specimens was 14.14%, the positive rate of influenza virus among diffe-rent years and age groups were both significantly different (both P<0.001). The main prevalent influenza strains from 2014 to 2023 included types A (H1N1), A (H3N2), B (Victoria), and B (Yamagata), alternating among di-fferent years. However, type B (Yamagata) strains were not detected from 2020 to 2023. There were basically two influenza prevalence seasons every year, namely winter-spring and summer. Conclusion People <15 years old are the main population of influenza, and the prevalence peaks are in winter-spring and summer. From 2021 to 2023, the prevalence alternates mainly among 3 types: A (H1N1), A (H3N2), and B (Victoria).