红串红球菌感染1例报告并文献复习

Rhodococcus erythropolis infection: one cases report and literature review

摘要:

红串红球菌是低毒力的条件致病菌, 人类感染罕见, 国内尚缺乏报道。本文报告1例在糖尿病基础上以发热、肺结节为主要临床表现的病例, 经肺穿刺活检及宏基因组二代测序证实为红串红球菌感染, 在此基础上系统回顾国内外相关文献, 总结该菌感染的临床表现和诊治经验供国内外同行参考, 以期今后对该菌感染能及时正确的诊断和治疗。

Abstract:

Rhodococcus erythropolis is an opportunistic pathogen with low virulence, human infection of which is rare, with few reports in China. This article reports a case with fever and pulmonary nodules as the main clinical manifestations on the basis of diabetes, which was confirmed as Rhodococcus erythropolis infection by lung biopsy and metagenomic next-generation sequencing. Relevant literatures from China and abroad were systematically reviewed, clinical manifestations as well as diagnosis and treatment experience of the infection caused by this bacteria were summarized, providing reference for domestic and foreign peers, in order to enable timely and accurate diagnosis and treatment of Rhodococcus erythropolis infection in the future.