Actinotignum schaalii 血流感染1例及病原体鉴定报告

Actinotignum schaalii bloodstream infection and identification of pathogen: one case report

摘要:

Actinotignum schaalii是一种新型致病菌，可导致尿路感染和侵袭性感染。2022年贵黔国际总医院收治1例急性尿潴留患者血培养标本，采用基质辅助激光解吸电离飞行时间质谱（MALDI-TOF-MS）技术鉴定结果为Actinotignum schaalii，为兼性厌氧的革兰阳性球杆菌。该病例为国内首次血培养检出Actinotignum schaalii，该患者使用头孢他啶5 d后，感染症状明显减轻，感染指标恢复正常，患者未诉发热等不适，遂出院。结合国内外相关文献，探讨Actinotignum schaalii的临床特征、鉴定及治疗。

Abstract:

Actinotignum schaalii (A. shaalii) is an emerging pathogen that may cause urinary tract infection and invasive infection. In 2022, pathogen in a blood culture specimen from a patient with acute urinary retention admitted to Guiqian International General Hospital was identified as A. schaalii by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which is a facultative anaerobic Gram-positive coccobacillus. This case reported the first time that A. schaalii was detected in blood culture in China. After using ceftazidime for 5 days, infection symptoms of patient were significantly reduced, infection indicators returned to normal. Patient did not complain of fever and other discomfort and was discharged. This article discusses the clinical characteristics, identification and treatment of A. schaalii in combination with relevant literatures at home and abroad.