耳念珠菌感染与医院感染防控研究现状

Current situation of prevention and control of infection and healthcare-associated infection due to Candida auris

摘要:

耳念珠菌（Candida auris）是2009年首次发现的一种可引起侵袭性感染的多重耐药酵母菌，且具有如下特点：实验室传统的形态和生化检验方法难以将其鉴定，临床分离株通常为多重耐药菌，感染致死率高，在环境物体表面和定植人群中能长时间存在。该菌目前传播机制以及消毒措施尚不明确，30多个国家陆续有其感染病例和医院感染事件的报道，正逐渐成为一个新的全球性威胁。我国已有18例耳念珠菌感染病例的报道。为提示耳念珠菌医院感染传播的风险，帮助医疗机构完善医院感染防控方案，本文就耳念珠菌感染以及其医院感染防控现状作一综述。

Abstract:

Candida auris(C. auris) is a multidrug-resistant yeast which can cause invasive infection, it was first detected and reported in 2009. It is difficult to be identified through the laboratory traditional morphological and biochemical detection methods, clinical isolates of C. auris are usually multidrug-resistant and cause infection with high mortality rates, it can exist for a long time on environmental surface and colonized population. To date, transmission mechanisms and disinfection measures of C. auris remained unclear, more than 30 countries have successively reported cases of infection and healthcare-associated infection(HAI) due to C. auris, which is gradually becomes a new global threat. Eighteen cases of C. auris infection have been reported in China. In order to reveal the risk of C. auris HAI transmission and help medical institutions improve the prevention and control program for HAI, this paper reviews the current situation of prevention and control of infection and HAI due to C. auris.