感染防控助推抗菌药物合理应用

Improving rational use of antimicrobial agents by infection prevention and control

摘要:

目的评价采取感染防控措施对管理抗菌药物合理应用的效果。方法选取某院2011—2015年住院患者为研究对象，采取一系列感染防控干预措施，评价干预效果。结果实施综合干预措施后，手卫生依从率逐年提升，从2011年的38.17%提高至2015年的87.16%，差异有统计学意义（χ2＝48.50，P＜0.05）。医院感染发生率由1.45%下降至1.06%,差异有统计学意义（χ2＝42.50，P＜0.05）；2011—2015年医院抗菌药物使用强度分别为63.1、44.4、40.0、40.8、40.5，呈逐年下降趋势。结论采取有效的感染防控措施对推进抗菌药物合理应用管理具有明显效果，有利于降低抗菌药物的临床使用强度。

Abstract:

ObjectiveTo evaluate the efficacy of infection prevention and control measures on the management of rational use of antimicrobial agents.MethodsPatients who were admitted in a hospital from 2011 to 2015 were as the research object, a series of infection prevention and control intervention measure were taken,  efficacy of intervention measures were evaluated.ResultsAfter the implementation of comprehensive intervention measures, compliance rate of hand hygiene increased year by year, from 38.17% in 2011 to 87.16% in 2015, difference was statistically significant （χ2＝48.50, P＜0.05）. Incidence of healthcareassociated infection dropped from 1.45% to 1.06%, difference was statistically significant （χ2＝42.50, P＜0.05）； antimicrobial use density in 2011-2015 were 63.1, 44.4, 40.0, 40.8, and 40.5 respectively, which showed a decreasing tendency. ConclusionEffective infection prevention and control measures have obvious effect on promoting management of rational use of antimicrobial agents, it is helpful for reducing the clinical use density of antimicrobial agents.