某综合医院住院患者梅毒血清学检测结果分析

Syphilis serological detection results of inpatients in a general hospital

摘要:

目的了解某综合医院住院患者梅毒血清学检测结果，为进一步开展梅毒防治工作提供新思路。方法对2012年1月—2013年12月某综合医院梅毒血清学检测结果异常的住院患者的临床资料进行分析。结果2012年1月—2013年12月该院住院患者共164 442例，进行梅毒血清学筛查112 576例，梅毒血清学检测结果异常2 048例。梅毒血清学检测结果异常者以31～、41～岁年龄段为主（39.06%），其次是51～、61～岁年龄段（34.42%）和≥71岁年龄段（15.63%）；职业分布主要以无业/待业人员（34.08%）、农民（23.05%）、退休人员（19.19%）为主。全院36个临床科室均有梅毒血清学异常的住院患者，其中主要检出科室为呼吸内科（9.86%）、妇科（7.13%）、心内科（6.88%）等。传播途径以非婚性接触为主（56.79%）；梅毒血清学检测结果以梅毒螺旋体明胶凝结试验(TPPA)和快速血浆反应素环状卡片试验(RPR)均阳性（46.14%）、TPPA阳性和RPR阴性（43.31%）为主。隐性梅毒者860例，占41.99%。结论梅毒血清学检测结果异常患者现状不容乐观，主要集中在31～50岁年龄组，应加强梅毒防治知识的宣传与教育，落实梅毒防治管理政策，加大梅毒的筛查力度，防止梅毒流行与传播。

Abstract:

ObjectiveTo understand serological detection results of syphilis among hospitalized patients in a general hospital, and provide new ideas for further prevention and treatment of syphilis. MethodsClinical data of inpatients with abnormal serological detection results for syphilis in a hospital from January 2012 to December 2013 were analyzed. ResultsA total of 164 442 patients were admitted to a hospital from January 2012 to December 2013, 112 576 of whom were performed syphilis serological screening, 2 048 cases were with abnormal results of serological detection for syphilis. The abnormal serological detection results were mainly in patients of 31～ and 41～ years  （39.06%），followed by patients of 51～, 61～ years （34.42%）, and≥71 years （15.63%）；unemployed people（34.08%）, farmers（23.05%）, and retirees(19.19%) were the main population with abnormal results. The abnormal serological detection results distributed in all 36 departments, the main departments were departments of respiratory medicine（9.86%）, gynaecology（7.13%）, and cardiovascular internal medicine（6.88%）. Nonmarital sex is the main route of transmission（56.79%）; the main syphilis serological detection results were both positive for Treponema pallidum particle agglutination (TPPA)assay and rapid plasma reagin (RPR) （46.14%）, as well as TPPA positive and RPR negative （43.31%）. 860 (41.99%) patients were with latent syphilis. ConclusionThe current status of patients with abnormal serological detection results of syphilis is not optimistic, mainly concentrated in patients of 31-50 years. It is necessary to strengthen publicity and education on prevention and treatment of syphilis, implement syphilis prevention and treatment policy, intensity syphilis screening， so as to prevent the epidemic and spread of syphilis.