420例结直肠癌患者手术部位感染状况及影响因素分析

Infection status and influencing factors of surgical site infection in 420 colorectal patients

摘要:

目的探讨结直肠癌患者手术部位感染状况及其影响因素。方法采用回顾性调查方法，对某院2007年1月—2011年12月间420例结直肠癌手术患者病历资料进行分析。结果420例结直肠癌患者手术部位感染率为20.24%（85/420）；以表浅切口感染为主，占75.29%（64/85），深部切口感染占22.35%（19/85），器官腔隙感染占2.35%（2/85）。共分离病原菌98株，以大肠埃希菌为主（55株，56.13%）。超重或肥胖（BMI≥23）、合并糖尿病、手术持续时间＞3.5 h、Dukes分期高的结直肠癌患者手术部位感染发生率显著升高（均P＜0.05）。结论结直肠癌患者手术部位感染率较高。超重或肥胖、合并糖尿病、手术持续时间长和Dukes分期高是结直肠癌患者手术部位感染的重要影响因素。

Abstract:

ObjectiveTo evaluate the status and influencing factors of surgical site infection(SSI) in colorectal cancer patients.MethodsA retrospective investigation was conducted to analyze the medical records of 420 colorectal cancer patients who were hospitalized between January 2007 and December 2011.ResultsSSI rate in 420 patients was 20.24 % (85/420); 75.29%(64/85) were superficial incisional infections, 22.35%(19/85) were deep incisional infections, 2.35%(2/85) were organ space infections. A total of 98 pathogenic strains were isolated, 56.13% (55 isolates) were Escherichia coli. The incidence of SSI increased significantly in patients with overweight or obesity (BMI≥23), diabetes mellitus, operative duration more than 3.5 h and high Dukes stage (all P<0.05).ConclusionSSI rate in colorectal cancer patients is high. Overweight or obesity, diabetes mellitus, long operative duration and the high Dukes stage are important factors for SSI in colorectal cancer patients．