2型糖尿病患者医院感染相关因素

Related factors for infections in patients with type 2 diabetes mellitusCHEN Qing

摘要:

目的研究2型糖尿病患者医院感染的相关因素，以制定相应对策，降低其感染率。方法选择2型糖尿病发生医院感染者48例（医院感染组）和同期住院未发生医院感染的2型糖尿病患者55例（对照组），比较2组患者入院时年龄、空腹血糖、糖化血红蛋白、住院时间、免疫水平、入院后侵袭性操作、抗菌药物及胰岛素泵使用情况。结果入院时医院感染组患者平均年龄（62.57±14.35）岁、空腹血糖（10.26±3.68）mmol/L、糖化血红蛋白（8.38±2.95）%、住院时间（21.38±10.77）d，均高于对照组［分别为（44.40±12.82）岁、（8.96±2.92）mmol/L、（6.73±2.57）%、（16.24±9.62）d］，差异均有统计学意义（P＜0.05）；免疫性指标差异无统计学意义（P＞0.05）；医院感染组患者进行侵袭性操作率（16.67%）、使用抗菌药物种类 ≥2种比率（68.75%）均高于对照组（分别为3.64%、9.09%），对照组胰岛素泵使用率（67.27%）高于医院感染组（14.58%），差异均有统计学意义（P＜0.05）。结论2型糖尿病患者医院感染可受多种因素的影响，应加强监测，针对相关因素采取综合性措施，防止其医院感染的发生。

Abstract:

ObjectiveTo study the related factors and appropriate strategies for infections in patients with type 2 diabetes mellitus (DM)，so as to reduce nosocomial infection(NI) rate.MethodsFortyeight type 2 DM patients with NI （NI group）and 55 type 2 DM patients without NI (control group) during the same hospitalization period were selected , patients’ age at admission , fasting blood sugar, glycohemoglobin, hospital stay, immunization level, invasive procedure , antimicrobial use , and continuous subcutaneous insulin infusion in two groups were compared .ResultsPatients’ average age at admission (［62.57±14.35］ years old), fasting blood sugar(［10.26±3.68］mmol/L), glycohemoglobin(［8.38±2.95］%), and hospital stay(［21.38±10.77］days) in NI group were higher than (［44.40±12.82］ years old), (［8.96±2.92］ mmol/L), (［6.73±2.57］%) ,and (［16.24±9.62］days) respectively in  control group,there was significant difference between two groups(all P<0.05);Immunization levels in two groups were not statistically significant(P>0.05); invasive  procedure rate in NI group (16.67%) and ≥2 typies of antimicrobial usage rate (68.75%) in NI group  were both higher than those (3.64%,9.09%) of control group  respectively, continuous subcutaneous insulin infusion rate  in control group(67.27%) was higher than that of NI group(14.58%), the difference was significant(P<0.05).ConclusionMultiple factors can influence the occurrence of NI in type 2 DM patients, surveillance should be intensified , comprehensive strategies should be taken to prevent the occurrence of NI.