内科重症监护室鲍曼不动杆菌医院感染危险因素病例对照研究 FREE

A casecontrol study on risk factors for nosocomial infection of Acinetobacter baumannii in internal medicine intensive care units FREE

摘要:

目的探讨内科重症监护室（ICU）患者鲍曼不动杆菌医院感染的危险因素。方法对某综合性三级甲等医院2007年1月1日—2008年12月31日所有发生鲍曼不动杆菌医院感染的ICU患者进行1∶2 匹配的病例对照研究，并采用条件Logistic回归分析。结果与鲍曼不动杆菌感染相关的危险因素为基础疾病个数（OR=4.03），留置鼻饲管（OR=11.37），使用呼吸机（OR=9.83），APACHE-Ⅱ（急性生理功能和慢性健康状况评分系统Ⅱ）评分（OR=1.20）；保护因素为使用维生素（OR=0.05）。结论改善患者的机体情况，增强患者的免疫力，减少各种侵入性操作，有利于预防和控制ICU鲍曼不动杆菌医院感染的发生。

Abstract:

ObjectiveTo explore the risk factors for nosocomial infection （NI）of Acinetobacter baummanii (A. baumannii) in patients in the internal medicine intensive care units (ICUs).MethodsA 1：2 matched casecontrol study was carried out in ICUs in a hospital between January 1,2007 and December 31,2008. Cases were patients with A. baumannii infections and controls were those without NI. Conditional Logistic regression analysis was performed to identify independent risk factors.ResultsThe independent risk factors were the number of the underlying diseases（OR=4.03）, duration of nasal feeding tube（OR=11.37）, using respirators（OR=9.83）and acute physiology and chronic health evaluation Ⅱ score system（OR=1.20）;  the protective factor was using vitamin（OR=0.05）.ConclusionImproving patients’ body state and immunity and reducing invasive procedures are helpful for the control and prevention of NI with A. baumannii in  patients in ICUs.
［Key words］intensive care unit；Acinetobacter baumannii；nosocomial infection；risk factors；casecontrol study